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李喜和教授简介

      现任5357cc拉斯维加斯首页入口教授/博士生导师/资源研究中心主任,同时任内蒙古赛科星繁育生物技术(集团)股份有限公司首席科学家/研究院院长、英国剑桥大学Gurdon发育生物学研究所兼职研究员。1984年本科毕业于内蒙古大学生物系动物学专业,1986-1989年硕士在读期间参加了导师旭日干院士主持的中国首例试管牛、羊的科研工作;1990年到日本东京农业大学攻读博士学位,师从日本生殖生物学会会长中原达夫教授,主要从事牛体外受精、显微受精和牛胚胎性别鉴定方面的基础研究,于1994年获得博士学位并在日本家畜改良技术研究所从事三年博士后研究。1998-2005年转入英国剑桥大学临床兽医系任高级研究员,从事马受精生物学研究与繁育生物技术开发。

在国内外主持和参加各种科技项目30余项,发表以生殖生物学研究和繁育生物技术开发为主的学术论文140余篇,进行学术会议讲演60余次,授权18项专利(包括15项发明专利、2项实用新型专利、1项国际发明专利PCT)、制定6项国家和行业标准,出版、再版专著3部。曾任日本东京农业大学中国学联会长;英国剑桥大学中国学联第二届学术委员会主任;日本家畜繁殖生物学会会员、英国受精生物学学会会员、美国生殖生物学会会员、中国奶业协会繁殖委员会副主任、内蒙古生物工程学会理事长、内蒙古侨联副主席、内蒙古欧美同学会常务理事。

 曾获2002年度剑桥中国学生学者联合会特别学术成果奖、2005年度内蒙古科教兴区突出贡献奖、2006年度内蒙古科技创新杰出引进人才奖、2007年度内蒙古中青年科技创新奖、2007年度与2014年度分别获得内蒙古科技进步一等奖2项,2007年入选国家级新世纪百千万人才工程,享受国务院政府特殊津贴。此外2009-2019分别年获得呼和浩特市市长特别奖、呼和浩特市科技进步一等奖4项、中国发明专利奖、中国侨界创新人才奖、中国侨界创新成果奖、十一五国家科技计划执行突出贡献奖、内蒙古大学科技创新奖、内蒙古农牧业丰收奖一等奖、内蒙古首届草原英才首届科技标兵,并且在2010年获得内蒙古最高科技奖励-内蒙古科学技术特别贡献奖。

邮箱:lixh@imu.edu.cn

 

现在研究领域:

1、家畜受精生物学研究与性别控制新技术开发应用

2、家畜干细胞诱导与育种新技术模型建立

3、蒙古高原动物遗传资源与动物杂交生殖调控机制研究

 

部分代表性科学论文:  

1. Baojiang Wu, Lin Li, Bojiang Li, Junpeng Gao, Yanglin Chen, Mengyi Wei, Zhiqing Yang, Baojing Zhang, Shudong Li, Kexin Li, Changshan Wang, M. Azim Surani, Xihe Li, Fuchou Tang, and Siqin Bao. Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media. Stem Cell Reports. 2020, 14: 241-255.

2. Jindun Zhang, Xuefei Gao, Jian Yang, Xiaoying Fan, Wei Wang, Yanfeng Liang, Lihong Fan, Hongmei Han, Xiaorong Xu, Fuchou Tang, Siqin Bao, Pentao Liu, Xihe Li*. Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice. Stem Cells, 2019, 37(5): 599-608.

3. Jian Zhang, Jie Su, Shuxiang Hu, Jindun Zhang, Rui Ding, Jitong Guo, Guifang Cao, Rongfeng Li, Qing Yuan Sun , Xihe Li*. Correlation between ubiquitination and defects of bull spermatozoa and removal of defective spermatozoa using anti-ubiquitin antibody-coated magnetized beads. Animal Reproduction Science, 2018, 192:44.

4. Siqin Bao, Walfred WC Tang, Baojiang Wu, Shinseog Kim, Jingyun Li, Lin Li, Toshihiro Kobayashi, Caroline Lee, Yanglin Chen, Mengyi Wei, Shudong Li, Sabine Dietmann, Fuchou Tang, Xihe Li*, M Azim Surani*. Derivation of hypermethylated pluripotent embryonic stem cells with high potency. Cell Research, 2018,10:1-13.

5. Lixia Zhao, Zixin Wang, Jindun Zhang, Jian Yang, Xuefei Gao, Baojiang Wu, Gaoping Zhao, Siqin Bao, Shuxiang Hu, Pentao liu, Xihe Li*. Characterization of the single-cell derived bovine induced pluripotent stem cells. Tissue and Cell, 2017,5(5):1-7.

6. Baojiang Wu, Lixia Zhao, Chengcheng Zhu, Yanglin Chen, Mengyi Wei, Siqin Bao, Shaochen Sun*, XiHe Li*. Altered apoptosis/autophagy and epigenetic modifications cause the impaired postimplantation octaploid embryonic development in mice. Cell Cycle, 2017, 16(1): 82-90.

7. Hongmei Han, Aihong Wang, Liming Liu, Gaoping Zhao, Jie Su,Biao Wang, Yunxia Li, Jindun Zhang, Baojiang Wu, Wei Sun, Shuxiang Hu, Shuyu Li, Lixia Zhao, Xihe Li*. Testicular characteristics and the block to spermatogenesis in mature hinny. Asian-Australasian Journal of Animal Sciences, 2016, 29(6):793-800.

8. Huamin GUOShuyu LiHongmei HANJindun ZHANGYanglin CHENLihong FANLixia ZHAOXihe LI*. Cloning, and Analysis of DDX3Y Gene Sequences of Male EquusLinnaeusAnimals. Agricultural Biology, 2015, 4(4):64-69.

9. Jian ZHANGHuamin GUOJie SULixia ZHAOYunxia LIWei SUNHongmei HANShuxiang HUGaoping ZHAOYao LIYanfeng DAIXihe LI*. A Comparison of the Effects of Pentoxifylline on Quality of Fresh and Frozen-thawed Bull Spermatozoa,  Agricultural Biotechnology , 2014, 3:20-24.

10. RHF. Hunter and Xihe Li*, Egg-Embryo Transfer: An Analytical Tool for Vintage Experiments in Domestic Farm Animals. Journal of Agricultural Science and Technology, 2013, 15(1):65-70.

11. S Bao, HG Leitch, FC Tang, A Gillich, J Nichols, S Kim, C Lee, Xihe Li and A Surani. The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells. Cell Stem Cell, 2012, 11:110-117.

12. S Bao, FC Tang, XH Li, K Hayashi, A Gillich, K Lao and A Surani. Epigenetic reversion of post —implantation epiblast to pluripotent embryonic stem cells. Nature, 2009, 461:1292-1295.

13. Xihe Li , SG Zhou, MP Imreh, L Ahrlund-Richter and WR Allen. ES cell lines obtained from proliferation of inner cell mass (ICM) cells of the horse blastocysts. Stem Cell and Development, 2006,15:523-531.

14. Xihe Li , LHA Morris and WR Allen. In vitro development of reconstructed horse oocytes following by nuclear transfer using fetal and adult cells. Biology of Reproduction , 2002 66:1288-1292.

15. Xihe Li , LHA Mooris and WR Allen. The influence of co-culture during maturation on the developmental potential of equine oocytes fertilized by intracytoplasmic sperm injection (ICSI). Reproduction, 2001 121:925-932.

16. K. Hamano, Xihe Li , X-Q. Qian, K. Funauchi, M. Furudate and Y. Minato. Gender preselection in cattle with intracytoplasmically injected, flow cytometrically sorted sperm heads. Biology of Reproduction, 1999, 60:1194-1197.

17. Bou Shorgan, Zhang Suolian, Liu Dongjun, Wang Jianguo, He Muren, Chan Hongwu, Yan Wenlong and Li Xihe*. Production of live offspring from Chinese Inner Mongolian white kid oocytes using superovulation and in vitro embryo production techniques. Japanese Journal of Embryo Transfer, 19:1-6, 1996.

18. X.Li, S. Iwasaki and T. Nakahara. Investigation of various conditions in microinjection of bovine oocytes and subsequent changes in nuclei and development to embryos. Journal of Reproduction and Development, 1994,39:49-55.

19. X.Li, S. Iwasaki and T. Nakahara. Effects of trophectoderm dissection on development of inner cell mass of fresh and frozen-thawed bovine blastocysts derived from in-vitro fertilization. Journal of Reproduction and Development, 1993, 39:281-286.

20. B. Shorgan, S. Zhang, X. Xue, Y. Pang, H. Chang, X. Li, Q. Hai, B. Siqin. In vitro development of ovine oocytes matured and fertilized in vitro and lambing after embryo transfer. Japanese Journal of Animal Reproduction, 1990, 36:225-230.

 

出版专著:  

1.《家畜性别控制技术》,主编,2009初版、2013再版,科学出版社。

2.《现代畜禽养殖技术》,参编,2014初版,中国农业出版社。

3.《牛冷冻精液生产与检测技术》,参编,2015初版,江苏凤凰科学技术出版社。 

 

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